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An ultraminiaturized platform utilizing commercially available automation and flow cytometry enables automated DNA-encoded library synthesis and activity-based screening at the attomole scale, increasing the accessibility of OBOC-DEL technology. Novelty: ClaimNovelty.METHODOLOGICAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

July 21, 2026Journal of Medicinal Chemistry0 citations

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Automated DNA-Encoded Library Synthesis and Activity-Based Screening at the Attomole Scale

JBJohn P. Burdick EAErika M. Cerna Arroyo SLSamantha R. Levine

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Abstract

class = 14). This ultraminiaturized platform uses commercially available automation and flow cytometry, making OBOC-DEL technology broadly accessible and distributable.

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Automated DNA-Encoded Library Synthesis and Activity-Based Screening at the Attomole Scale

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