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Target practice: A novel photodynamic therapy system has been constructed by taking advantage of the specific molecular recognition of an aptamer, loading capability of a G-quadruplex, and upconversion of nanoparticles using near-infrared (NIR) light. This system selectively delivers a photosensitizer to targeted cells and upon irradiation with NIR light demonstrates phototoxicity effects.
Yuan et al. (Tue,) studied this question.