Chiral Phosphinoaryldihydrooxazoles as Ligands in Asymmetric Catalysis: Pd‐Catalyzed Allylic Substitution

Enantioselectivities up to 99% ee and excellent yields under mild reaction conditions could be realized in allylic alkylations Eq. (a) with palladium catalysts prepared with the chiral ligands 1. Enantiomerically pure phosphinoaryldihydrooxazoles (1) are readily accessible from commercially available chiral amino alcohols. HNu = H2C(COOMe)2, H2C(COMe)2, HC(NHAc)(COOEt)2.