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我们最近证明，结肠通过一层内层黏液保护，能够有效地将外层黏液中的细菌与上皮细胞隔离。内层黏液对细菌不透，并由MUC2粘蛋白形成的网络构成。缺乏或该内层黏液的缺陷使细菌能够到达上皮细胞，从而引发结肠炎症.
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Hansson 等人（周五）研究了这个问题.