Recent Progress in Situ Application of H2O2 Produced via Catalytic Synthesis

Abstract Industrial production of H 2 O 2 requires lots of energy and causes environmental pollution. Moreover, in subsequent applications, much economic loss could be produced during the transportation process of H 2 O 2 and its dilution process. Therefore, it is highly desirable for in situ application of H 2 O 2 . In recent years, catalytic synthesis of H 2 O 2 , e. g., direct catalytic synthesis, electrocatalytic synthesis, and photocatalytic synthesis, has attracted more and more attention because the continuous and low‐concentration H 2 O 2 produced by catalytic synthesis can be directly used for the oxidation of organic compounds, effectively avoiding the shortcomings of the current industrial route. Here, we briefly reviewed the latest processes for the catalytic production of H 2 O 2 via various routes. On this basis, we summarized and discussed the in situ application of H 2 O 2 in typical organic conversion reactions, including the ammoximation of ketones, the oxidation of alcohols, the oxidation of C−H bonds, and the oxidation of olefins. Some in situ coupling reactions have shown excellent performance with high conversion and selectivity, and the economic cost has been significantly reduced. Finally, the shortcomings of the in situ utilization of H 2 O 2 in coupling reactions were analyzed, and some strategies for promoting the efficiency of the H 2 O 2 application in organic synthesis were proposed.