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October 1, 2011Physiology164 citations

Driving With No Brakes: Molecular Pathophysiology of Kv7 Potassium Channels

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MSMaria Virginia SoldovieriFMFrancesco MiceliMTMaurizio Taglialatela

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Abstract

Kv7 potassium channels regulate excitability in neuronal, sensory, and muscular cells. Here, we describe their molecular architecture, physiological roles, and involvement in genetically determined channelopathies highlighting their relevance as targets for pharmacological treatment of several human disorders.

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Cite This Study

Soldovieri et al. (2011) studied this question. Kv7 potassium channels regulate cellular excitability and are involved in genetic channelopathies, making them relevant pharmacological targets for treating several human disorders.

synapsesocial.com/papers/6a6c89da35aa2c282cdf9583https://doi.org/10.1152/physiol.00009.2011
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