Key result
Kv7 potassium channels regulate cellular excitability and are involved in genetic channelopathies, making them relevant pharmacological targets for treating several human disorders.
Key points are not available for this paper at this time.
Design
Review
Supports Kv7 channels as pharmacological targets in channelopathies; leaves open clinical translation to cardiovascular disease.
Kv7 potassium channels regulate excitability in neuronal, sensory, and muscular cells. Here, we describe their molecular architecture, physiological roles, and involvement in genetically determined channelopathies highlighting their relevance as targets for pharmacological treatment of several human disorders.
No takes yet. Share an insight, caveat, or question.
Soldovieri et al. (2011) studied this question. Kv7 potassium channels regulate cellular excitability and are involved in genetic channelopathies, making them relevant pharmacological targets for treating several human disorders.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: