Key result
Pharmacological targeting of KCNQ-encoded Kv7 channels presents a broad therapeutic appeal due to their physiological impact and involvement in hereditary disorders.
Design
Review
Authors
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Kv7 modulators merit cautious exploration in channelopathies; leaves open clinical efficacy pending randomized trials.
Pharmacological targeting of KCNQ-encoded Kv7 potassium channels presents a broad therapeutic appeal due to their physiological impact and role in hereditary disorders.
Barrese et al. (2017) conducted a review in Hereditary disorders caused by mutations to KCNQ genes. Pharmacological targeting of Kv7 channels was evaluated. Pharmacological targeting of KCNQ-encoded Kv7 channels presents a broad therapeutic appeal due to their physiological impact and involvement in hereditary disorders.
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