Concurrent atrial fibrillation in patients undergoing PVC ablation was associated with a higher 2-year PVC recurrence rate compared to those without AF (17.7% vs. 9.4%, p=0.02).
Cohort
No
Does concurrent atrial fibrillation increase the risk of PVC recurrence in patients undergoing catheter ablation for premature ventricular complexes?
Concurrent atrial fibrillation in patients undergoing PVC ablation is associated with a higher rate of long-term PVC recurrence, likely driven by older age, worse LV function, and multiple PVC morphologies.
Absolute Event Rate: 17.7% vs 9.4%
p-value: p=0.02
INTRODUCTION: Atrial fibrillation (AF) and premature ventricular complexes (PVC) are common arrhythmias. We aimed to investigate AF prevalence in patients with PVC and its impact on PVC ablation outcomes. METHODS: Consecutive patients undergoing PVC ablation at a single institution between 2016 and 2019 were included and prospectively followed for 2 years. Patients with severe valvular heart disease, hyperthyroidism, malignancy, alcohol use disorder and advanced renal/hepatic diseases were excluded. Twelve-lead electrocardiograms were used to diagnose AF and assess PVC morphology. All PVCs were targeted for ablation using 4-mm irrigated-tip catheters at standardized radiofrequency power guided by 3-D mapping and intracardiac echocardiography. Patients were followed with remote monitoring, device interrogations and office visits every 6 months for 2 years. Detection of any PVCs in follow-up was considered as recurrence. RESULTS: -VASc (2.8 ± 1.3 vs. 2.0 ± 1.3, p < .001) than those without. PVCs with ≥2 morphologies were detected in 60.4% and 13.7% patients with vs without AF (p < .001). At 2-year follow-up, PVC recurrence rate was significantly higher in patients with vs without AF (17.7% vs. 9.4%, p = .02). CONCLUSION: AF was documented in 1/4 of patients undergoing PVC ablation and was associated with lower procedural success at long-term follow-up. This was likely attributed to older age, worse LV function and higher prevalence of multiple PVC morphologies in patients with concurrent AF.
Zou et al. (Tue,) conducted a cohort in Premature ventricular complexes (PVC). Concurrent atrial fibrillation vs. No atrial fibrillation was evaluated on PVC recurrence (detection of any PVCs in follow-up) (p=0.02). Concurrent atrial fibrillation in patients undergoing PVC ablation was associated with a higher 2-year PVC recurrence rate compared to those without AF (17.7% vs. 9.4%, p=0.02).