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April 30, 2014Clinical and Experimental Hypertension2 citations

Association of N-terminal pro-brain natriuretic peptide and hemodynamic parameters measured by impedance cardiography in patients with essential hypertension

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PKPaweł KrzesińskiGGGrzegorz GielerakASAdam Stańczyk

Key Result

NT-proBNP levels in patients with arterial hypertension correlated positively with Heather index (r=0.375, p<0.00001) and negatively with thoracic fluid content (r=-0.300, p=0.0002).

Study Design

Type

Cross-Sectional (n=156)

Structured PICO

P
Population
156 patients with arterial hypertension evaluated for the association of NT-proBNP with clinical and hemodynamic parameters.
O
Outcome
Association of NT-proBNP with clinical and hemodynamic assessment (age, mean blood pressure, Heather index, thoracic fluid content)surrogate

In patients with essential hypertension, higher NT-proBNP levels are independently associated with older age, higher mean blood pressure, and higher Heather index measured by impedance cardiography.

Abstract

The aim of this study was to evaluate the association of NT-proBNP with clinical and hemodynamic assessment in 156 patients with arterial hypertension. NT-proBNP correlated positively with, i.e. age (r=0.310, p=0.00008), mean blood pressure (MBP; r=0.199, p=0.0136), Heather index (HI; r=0.375, p<0.00001) and negatively with thoracic fluid content (TFC; r=-0.300, p=0.0002). The patients with higher NT-proBNP were older (46.1 versus 40.6 years, p=0.001), with higher MBP (102.6 versus 98.5 mm Hg, p=0.0043), HI (14.54 versus 11.93 Ohm s2, p=0.009) and lower TFC (27.5 versus 29.4 1/kOhm, p=0.0032). The independent predictors of higher NT-proBNP were: age, MBP and HI.

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Cite This Study

Krzesiński et al. (2014) conducted a cross-sectional in arterial hypertension (n=156). NT-proBNP was evaluated on Association of NT-proBNP with clinical and hemodynamic parameters. NT-proBNP levels in patients with arterial hypertension correlated positively with Heather index (r=0.375, p<0.00001) and negatively with thoracic fluid content (r=-0.300, p=0.0002).

synapsesocial.com/papers/6a81b7f978e42fa194a1ec4ehttps://doi.org/10.3109/10641963.2014.913611
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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  5. 5Comprehensive Review of the Relative Clinical Utility of B-Type Natriuretic Peptide and N-Terminal Pro-B-Type Natriuretic Peptide Assays in Cardiovascular Disease2009 · 19 citations