Cross-Sectional (n=156)
In patients with essential hypertension, higher NT-proBNP levels are independently associated with older age, higher mean blood pressure, and higher Heather index measured by impedance cardiography.
NT-proBNP links to impedance markers in hypertension; hypothesis-generating and should not yet change practice.
The aim of this study was to evaluate the association of NT-proBNP with clinical and hemodynamic assessment in 156 patients with arterial hypertension. NT-proBNP correlated positively with, i.e. age (r=0.310, p=0.00008), mean blood pressure (MBP; r=0.199, p=0.0136), Heather index (HI; r=0.375, p<0.00001) and negatively with thoracic fluid content (TFC; r=-0.300, p=0.0002). The patients with higher NT-proBNP were older (46.1 versus 40.6 years, p=0.001), with higher MBP (102.6 versus 98.5 mm Hg, p=0.0043), HI (14.54 versus 11.93 Ohm s2, p=0.009) and lower TFC (27.5 versus 29.4 1/kOhm, p=0.0032). The independent predictors of higher NT-proBNP were: age, MBP and HI.
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Krzesiński et al. (2014) conducted a cross-sectional in arterial hypertension (n=156). NT-proBNP was evaluated on Association of NT-proBNP with clinical and hemodynamic parameters.
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