Serum NT-proBNP levels (mean 92.98 pg/ml) in systemic hypertensive patients increased proportionately with left ventricular mass and relative wall thickness.
Cross-Sectional (n=50)
No
Do serum NT-proBNP levels correlate with left ventricular hypertrophy in hypertensive patients?
Serum NT-proBNP levels correlate proportionately with left ventricular mass in hypertensive patients, suggesting its potential utility as a prognostic biomarker for imminent cardiac failure.
Introduction: Since they are important for assessing the risk of increased left ventricular volume and pressure, the cardiac marker N-terminal pro-brain natriuretic peptide (NT-proBNP) may be a reliable indicator of systemic hypertension and impending cardiac failure. Methodology: Fifty participants participated in a facility-based cross-sectional study at a tertiary healthcare center in Puducherry, India. The Chi-square test was used as a test of significance to examine the clinical relationship between NT-proBNP levels and left ventricular hypertrophy in hypertensive patients. A P < 0.05 was taken to be statistically significant. Results: The study participants’ NT-proBNP levels ranged from 10 to 400 pg/ml, with a mean of 92.98 pg/ml and a standard deviation 91. NT-proBNP levels were found to be statistically correlated with left ventricular mass and relative wall thickness. Conclusion: According to the study’s findings, systemic hypertensive patients’ serum NT-pro BNP level increases proportionately with their left ventricular mass as determined by a transthoracic echocardiogram (2D ECHO). As a result, it can be regarded as a prognostic biomarker for imminent cardiac failure, which will aid in a more accurate assessment of cardiovascular risk in hypertensive individuals.
Karthik et al. (Fri,) conducted a cross-sectional in Systemic hypertension with left ventricular hypertrophy (n=50). NT-proBNP measurement was evaluated on Correlation between NT-proBNP levels and left ventricular mass and relative wall thickness. Serum NT-proBNP levels (mean 92.98 pg/ml) in systemic hypertensive patients increased proportionately with left ventricular mass and relative wall thickness.