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August 8, 2022Russian Journal of Cardiology2 citationsOpen Access

Effect of catheter ablation for atrial fibrillation on left and right atrial function

TMT. V. MoskovskikhАСА. В. СморгонEAE. V. Archakov

Key Result

Catheter ablation for atrial fibrillation significantly reduced left atrial reservoir function by 6.45% (p<0.001) at 3 days post-procedure, with no significant change in right atrial contractility.

Study Design

Type

Observational (n=28)

Multicenter

No

Structured PICO

Does catheter ablation for atrial fibrillation affect left and right atrial function in the early postoperative period?

P
Population
28 patients (mean age 57.7 years, 50% female) with symptomatic paroxysmal or persistent atrial fibrillation refractory to antiarrhythmic therapy, evaluated before and 3 days after catheter ablation.
I
Intervention
Radiofrequency ablation (RFA) with pulmonary vein antrum isolation
C
Comparator
Baseline (before ablation)
O
Outcome
Change in left atrial reservoir, conduit and booster pump function and right atrial peak longitudinal strain assessed by 2D speckle tracking echocardiography at 3 days after ablationsurrogate

Catheter ablation for atrial fibrillation significantly impairs left atrial reservoir, conduit, and pump functions in the early postoperative period, while right atrial contractility remains unchanged.

Main Result

Mean Difference: -6.45

Absolute Event Rate: 19.23% vs 25.68%

p-value: p=<0.001

Limitations

  • Small sample size
  • Short follow-up period (3 days)
  • Single-center study
  • Requires further dynamic observation to track the timing of LA function recovery and RA function changes

Abstract

Aim . To evaluate the effect of catheter ablation on left (LA) and right atria (RA) function in patients with atrial fibrillation. Material and methods . The study included 28 patients (14 men and 14 women) aged 33 to 72 years (mean age, 57,7±9,9 years) with paroxysmal (n=23) and persistent AF (n=5). All patients underwent radiofrequency ablation (RFA) with pulmonary vein antrum isolation. Before ablation and 3 days after, transthoracic twodimensional echocardiography was performed in sinus rhythm with an assessment of LA reservoir, conduit and booster pump function and RA peak longitudinal strain. Results. In the studied patients, a significant decrease in the reservoir, conduit and booster pump function of the LA was revealed after RFA, while there was no significant change in RA peak longitudinal strain after catheter ablation. LA reservoir, conduit and booster pump function decreased by 6,45% (p<0,001), 3,59% (p<0,001), 2,85% (p<0,001), respectively, while RA peak longitudinal strain increased by 0,73% (p=0,43). Conclusion. Catheter ablation has a significant damaging effect on the LA tissue, inhibiting the reservoir, pumping and pipeline functions. At the same time, the contractility of the PP in the early postoperative period improves, but not significantly.

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Cite This Study

Moskovskikh et al. (2022) conducted an observational in Atrial fibrillation (n=28). Catheter ablation (radiofrequency ablation) vs. Baseline (before ablation) was evaluated on Left atrial reservoir function (decrease of 6.45%, p=<0.001). Catheter ablation for atrial fibrillation significantly reduced left atrial reservoir function by 6.45% (p<0.001) at 3 days post-procedure, with no significant change in right atrial contractility.

synapsesocial.com/papers/6a848eb8cdf3a848bdbd9449https://doi.org/10.15829/1560-4071-2022-5087
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