Key result
Catheter ablation for atrial fibrillation significantly reduced left atrial reservoir function by 6.45% (p<0.001) at 3 days post-procedure, with no significant change in right atrial contractility.
Why the study?
The study was conducted to evaluate the effect of catheter ablation on left and right atrial function in patients with atrial fibrillation.
Does catheter ablation for atrial fibrillation affect left and right atrial function in the early postoperative period?
Observational (n=28)
No
Does catheter ablation for atrial fibrillation affect left and right atrial function in the early postoperative period?
Mean Difference: -6.45
Absolute Event Rate: 19.23% vs 25.68%
p-value: p=<0.001
Catheter ablation for atrial fibrillation significantly impairs left atrial reservoir, conduit, and pump functions in the early postoperative period, while right atrial contractility remains unchanged.
Early post-ablation LA impairment may warrant closer monitoring; leaves open long-term durability and clinical impact.
Aim . To evaluate the effect of catheter ablation on left (LA) and right atria (RA) function in patients with atrial fibrillation. Material and methods . The study included 28 patients (14 men and 14 women) aged 33 to 72 years (mean age, 57,7±9,9 years) with paroxysmal (n=23) and persistent AF (n=5). All patients underwent radiofrequency ablation (RFA) with pulmonary vein antrum isolation. Before ablation and 3 days after, transthoracic twodimensional echocardiography was performed in sinus rhythm with an assessment of LA reservoir, conduit and booster pump function and RA peak longitudinal strain. Results. In the studied patients, a significant decrease in the reservoir, conduit and booster pump function of the LA was revealed after RFA, while there was no significant change in RA peak longitudinal strain after catheter ablation. LA reservoir, conduit and booster pump function decreased by 6,45% (p<0,001), 3,59% (p<0,001), 2,85% (p<0,001), respectively, while RA peak longitudinal strain increased by 0,73% (p=0,43). Conclusion. Catheter ablation has a significant damaging effect on the LA tissue, inhibiting the reservoir, pumping and pipeline functions. At the same time, the contractility of the PP in the early postoperative period improves, but not significantly.
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Moskovskikh et al. (2022) conducted an observational in Atrial fibrillation (n=28). Catheter ablation (radiofrequency ablation) vs. Baseline (before ablation) was evaluated on Left atrial reservoir function (decrease of 6.45%, p=<0.001). Catheter ablation for atrial fibrillation significantly reduced left atrial reservoir function by 6.45% (p<0.001) at 3 days post-procedure, with no significant change in right atrial contractility.
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