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October 1, 1972Journal of General Virology9 citations

Specific Inhibition of Poliovirus Induced Blockade of Cell Protein Synthesis by a Thiopyrimidine Derivative

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PCP. La CollaMMMaria Antonietta MarcialisGMGiampaolo Mereu

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Abstract

SUMMARY A thiopyrimidine derivative, i.e. ethyl-2-methylthio-4-methyl-5-pyrimidine carboxylate (S-7) is capable of preventing both poliovirus RNA synthesis and virus induced inhibition of cell protein synthesis.

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Cite This Study

Colla et al. (1972) studied this question.

synapsesocial.com/papers/6a85a22abeaf5c5b091091eahttps://doi.org/10.1099/0022-1317-17-1-13
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Inhibition of Poliovirus by Effect of a Methylthiopyrimidine Derivative1970 · 26 citations
  2. 2RELATIONSHIP BETWEEN STRUCTURE OF BENZIMIDAZOLE DERIVATIVES AND SELECTIVE VIRUS INHIBITORY ACTIVITY1961 · 71 citations
  3. 3Cytopathogenic Effect of Poliomyelitis Viruses In vitro on Human Embryonic Tissues.1950 · 81 citations
  4. 4STUDIES ON THE PROPAGATION IN VITRO OF POLIOMYELITIS VIRUSES1953 · 861 citations
  5. 5SPECTRUM AND CHARACTERISTICS OF THE VIRUS INHIBITORY ACTION OF 2-(α-HYDROXYBENZYL)-BENZIMIDAZOLE1961 · 138 citations