The A2B score, based on age, hemoglobin, and BNP at discharge, effectively stratified 2-year survival rates in patients with acute decompensated heart failure from 97.8% in the extremely low-risk group to 45.2% in the high-risk group.
Cohort (n=1,281)
Yes
Does the A2B risk score predict 2-year survival in patients discharged after acute decompensated heart failure?
The A2B score, utilizing age, hemoglobin, and BNP, provides a simple and effective tool for predicting 2-year survival in patients discharged after acute decompensated heart failure.
Effect estimate: C-statistic 0.711 (95% CI 0.671-0.751)
p-value: p=<0.0001
BACKGROUND: Prognosis after acute decompensated heart failure (ADHF) is poor. An appropriate risk score that would allow for improved care and treatment of ADHF patients after discharge, however, is lacking. METHODS AND RESULTS: B score (extremely low, 0; low, 1-2; medium, 3-4; high, 5-6). For the extremely low-risk group, the 2-year survival rate was 97.8%, compared with 84.5%, 66.1%, and 45.2% for the low-, medium-, and high-risk groups, respectively. Using the JCARE-CARD as a validation model, for the extremely low-risk group, the 2-year survival was 95.4%, compared with 90.2%, 75.0%, and 55.6% for the low-, medium-, and high-risk groups, respectively. CONCLUSIONS: B score is useful for estimating survival rate in ADHF patients at discharge.
Nakada et al. (2019) conducted a cohort in Acute Decompensated Heart Failure (ADHF) (n=1,281). A2B score (Age, Hemoglobin, BNP) vs. Different risk strata (extremely low, low, medium, high) was evaluated on All-cause death during 2-year follow-up, excluding in-hospital death (C-statistic 0.711, 95% CI 0.671-0.751, p=<0.0001). The A2B score, based on age, hemoglobin, and BNP at discharge, effectively stratified 2-year survival rates in patients with acute decompensated heart failure from 97.8% in the extremely low-risk group to 45.2% in the high-risk group.