Key result
The A2B score, based on age, hemoglobin, and BNP at discharge, effectively stratified 2-year survival rates in patients with acute decompensated heart failure from 97.8% in the extremely low-risk group to 45.2% in the high-risk group.
Why the study?
Prognosis after acute decompensated heart failure is poor, and an appropriate risk score to improve post-discharge care and treatment is lacking.
Does the A2B risk score predict 2-year survival in patients discharged after acute decompensated heart failure?
Cohort (n=1,281)
Yes
Does the A2B risk score predict 2-year survival in patients discharged after acute decompensated heart failure?
Answers are grounded in this paper and cite their sources.
The A2B score, utilizing age, hemoglobin, and BNP, provides a simple and effective tool for predicting 2-year survival in patients discharged after acute decompensated heart failure.
BACKGROUND: Prognosis after acute decompensated heart failure (ADHF) is poor. An appropriate risk score that would allow for improved care and treatment of ADHF patients after discharge, however, is lacking. METHODS AND RESULTS: B score (extremely low, 0; low, 1-2; medium, 3-4; high, 5-6). For the extremely low-risk group, the 2-year survival rate was 97.8%, compared with 84.5%, 66.1%, and 45.2% for the low-, medium-, and high-risk groups, respectively. Using the JCARE-CARD as a validation model, for the extremely low-risk group, the 2-year survival was 95.4%, compared with 90.2%, 75.0%, and 55.6% for the low-, medium-, and high-risk groups, respectively. CONCLUSIONS: B score is useful for estimating survival rate in ADHF patients at discharge.
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Nakada et al. (2019) conducted a cohort in Acute Decompensated Heart Failure (ADHF) (n=1,281). A2B score (Age, Hemoglobin, BNP) vs. Different risk strata (extremely low, low, medium, high) was evaluated on All-cause death during 2-year follow-up, excluding in-hospital death (C-statistic 0.711, 95% CI 0.671-0.751, p=<0.0001). The A2B score, based on age, hemoglobin, and BNP at discharge, effectively stratified 2-year survival rates in patients with acute decompensated heart failure from 97.8% in the extremely low-risk group to 45.2% in the high-risk group.
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