A Clinical Study of Malignant Hypertension

Article1 January 1939A CLINICAL STUDY OF MALIGNANT HYPERTENSIONIRVINE H. PAGE, M.D.IRVINE H. PAGE, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-12-7-978 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptPhysicians have long recognized that the clinical course of arterial hypertension is exceptionally variable. The lives of some patients appear to be little shortened by elevated blood pressure while others succumb within periods measurable in months. Volhard and Fahr (1914) emphasized these differences by the terms "benign" and "malignant," and Volhard pointed out that the benign form of hypertension may at any time turn malignant.For some years the genesis of hypertension which showed signs of a rapidly fatal outcome was ascribed to the kidneys. Scant regard was paid the blood vessels in the remainder of the body. The morbid...References1. DEROWALTSCHULE HAMD: Malignant hypertension, N. Eng. Jr. Med., 1935, ccxiii, 951-960. CrossrefGoogle Scholar2. ELLIS LB: Clinical course of malignant hypertension, Med. Clin. N. Am., 1932, xv, 1025-1039. Google Scholar3. ELLIS A: Malignant hypertension (Schorstein Lecture), Lancet, 1938, i, 977-980. CrossrefGoogle Scholar4. FAHR T: Ueber Nephrosklerose, Virchow's Arch. f. path. Anat., 1919, ccxxvi, 119-178. CrossrefGoogle Scholar5. FISHBERGOPPENHEIMER AMBS: The differentiation and significance of certain ophthalmoscopic pictures in hypertensive diseases, Arch. Int. Med., 1930, xlvi, 901-920. CrossrefGoogle Scholar6. GOLDBLATT H: Studies on experimental hypertension. VII. Production of the malignant phase of hypertension, Jr. Exper. Med., 1938, lxvii, 809-825. CrossrefGoogle Scholar7. KEITHWAGENERKERNOHAN NMHPJW: Syndrome of malignant hypertension, Arch. Int. Med., 1928, xli, 141. WAGENER, H. P., and KEITH, N. M.: Cases of marked hypertension, adequate renal function and neuroretinitis, Arch. Int. Med., 1924, xxxiv, 374-387. CrossrefGoogle Scholar8. KLEMPEREROTANI PS: Malignant nephrosclerosis (Fahr), Arch. Path., 1931, xi, 60-117. Google Scholar9. KEYESGOLDBLATT JEH: Experimental hypertension. Clinical and pathological studies of the eye: preliminary report, Arch. Ophth., 1937, xvii, 1040-1054. CrossrefGoogle Scholar10. MURPHYGRILL FDJ: So-called malignant hypertension: clinical and morphological study, Arch. Int. Med., 1930, xlvi, 75-104. CrossrefGoogle Scholar11. PAGE IH: Syndrome simulating diencephalic stimulation occurring in patients with essential hypertension, Am. Jr. Med. Sci., 1935, cxc, 9-14. CrossrefGoogle Scholar12. PAGEHEUER IHGJ: Treatment of essential and malignant hypertension by section of anterior nerve roots, Arch. Int. Med., 1937, lix, 245-298. CrossrefGoogle Scholar13. PAGEHEUER IHGJ: Effect of splanchnic nerve resection on patients suffering from hypertension, Am. Jr. Med. Sci., 1937, cxciii, 820-841. CrossrefGoogle Scholar14. VAN SLYKERHOADSHILLERALVING DDCPAAS: Relationship of urea clearance to renal blood flow, Am. Jr. Physiol., 1934, cx, 387-391. CrossrefGoogle Scholar15. VOLHARDFAHR FT: Die Brightsche Nierenkrankheit, Klinik, Pathologie und Atlas, 1914, J. Springer, Berlin. CrossrefGoogle Scholar16. VOLHARD F: Die doppelseitigen hämatogenen Nierenkrankungen (Brightsche Krankheit), 1918, J. Springer, Berlin. CrossrefGoogle Scholar17. WAGENER HP: Retinal vascular changes in hypertension, ANN. INT. MED., 1930, iv, 222-226. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication June 3, 1938.From the Hospital of the Rockefeller Institute for Medical Research, New York, N. Y. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byMalignant Nephrosclerosis in Patients with Hemolytic Uremic Syndrome (Primary Malignant Nephrosclerosis)SURVIVAL AND MORTALITY IN MALIGNANT (GRADE IV) AND GRADE III HYPERTENSIONZur Pathogenese der sogenannten malignen HypertonieEssential HypertensionHypertonieHypertonieIncidence of Various Types of Cardiovascular Diseases by age Group in the Male and in the Female†THE EVALUATION OF ANTIHYPERTENSIVE PROCEDURES, WITH PARTICULAR REFERENCE TO THEIR EFFECTS ON BLOOD PRESSURE*A. C. CORCORAN, M.D., F.A.C.P., HARRIET P. DUSTAN, M.D., IRVINE H. PAGE, M.D., F.A.C.P.The natural history and course of hypertension with papilledema (Malignant Hypertension)SYMPATHECTOMY IN THE TREATMENT OF HYPERTENSION REVIEW OF 122 CASESMalignant HypertensionMalignant Primary Nephrosclerosis of a Series of Hospital Patients.Hypertensive Vascular Disease: Its Clinical Course, Differential Diagnosis, Pathogenesis and Treatment 1 January 1939Volume 12, Issue 7Page: 978-1004KeywordsBlood pressureBlood vesselsHypertensionKidneys ePublished: 1 December 2008 Issue Published: 1 January 1939 PDF downloadLoading ...