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March 8, 2021JAMA Network Open17 citationsOpen Access

Off-label Use of Direct Oral Anticoagulants in Patients Receiving Surgical Mechanical and Bioprosthetic Heart Valves

AKAnkur KalraSRSajjad RazaBJBaqir Jafry

Structured PICO

Does direct oral anticoagulant use differ from warfarin in preoperative and postoperative profiles in patients with surgical prosthetic heart valves?

P
Population
Patients with surgical mechanical and bioprosthetic heart valves in the United States
I
Intervention
Direct oral anticoagulants (DOACs)
C
Comparator
Warfarin
O
Outcome
Differences in preoperative and postoperative profiles

This study evaluates the off-label use and patient profiles of direct oral anticoagulants compared to warfarin in patients with surgical prosthetic heart valves.

Abstract

This cohort study assesses direct oral anticoagulant use in patients with surgical prosthetic heart valves in the United States and evaluates differences in preoperative and postoperative profiles in patients discharged while receiving direct oral anticoagulant vs warfarin.

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Cite This Study

Kalra et al. (2021) studied this question.

synapsesocial.com/papers/6a9683bdc00de92d9bfbbe62https://doi.org/10.1001/jamanetworkopen.2021.1259
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