Why the study?
To assess direct oral anticoagulant use in patients with surgical prosthetic heart valves in the United States and evaluate differences in profiles between those discharged on direct oral anticoagulants versus warfarin.
Does direct oral anticoagulant use differ from warfarin in preoperative and postoperative profiles in patients with surgical prosthetic heart valves?
Does direct oral anticoagulant use differ from warfarin in preoperative and postoperative profiles in patients with surgical prosthetic heart valves?
This study evaluates the off-label use and patient profiles of direct oral anticoagulants compared to warfarin in patients with surgical prosthetic heart valves.
Off-label DOAC use after prosthetic valve surgery warrants caution; extends real-world patterns in bioprosthetic valves but leaves efficacy and safety unaddressed.
This cohort study assesses direct oral anticoagulant use in patients with surgical prosthetic heart valves in the United States and evaluates differences in preoperative and postoperative profiles in patients discharged while receiving direct oral anticoagulant vs warfarin.
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Kalra et al. (2021) studied this question.
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