Closed mitral valvulotomy was associated with a lower incidence of late arterial emboli compared to unoperated management in patients with mitral stenosis (1.0% vs 3.7% per patient-year).
Cohort (n=526)
Absolute Event Rate: 1% vs 3.7%
During an average period of follow-up of 6 years, 255 patients subjected to closed mitral valvulotomy had an incidence of late arterial emboli of 1.0% per patient-year. In an unoperated series of 271 patients with mitral stenosis the incidence was 3.7% per patient-year. The significant protective value of mitral valvulotomy against late systemic embolism was particularly evident in patients with pre-operative atrial fibrillation. In subjects with pre-operative arterial emboli the rate of late embolism was 3.0% per patient-year, and it is suggested that long-term anticoagulant therapy is considered in this group of patients.
Olesen et al. (1972) conducted a cohort in Mitral stenosis (n=526). Closed mitral valvulotomy vs. Unoperated was evaluated on Late arterial emboli. Closed mitral valvulotomy was associated with a lower incidence of late arterial emboli compared to unoperated management in patients with mitral stenosis (1.0% vs 3.7% per patient-year).