Figure 6 from PSA Secretion from Single Circulating Tumor Cells of Metastatic Castration-Naïve Prostate Cancer Patients

PSA secretions (pg/cell) from single CTC and total CTC captured in nanowell array from patients with mCNPC (n = 18). A, The PSMA+ PSA+ (in red) and PSMA−PSA+ (in yellow) indicate the two subpopulations of CTC that secrete. The PSMA+ PSA− (in green) and PSMA−PSA− (in blue) indicate the two subpopulations of CTC that are non-secreting cells. The serum PSA (ng/mL) and the CTC in 7.5 mL of blood are indicated on the secondary x-axis. B, Total counts of the CTC captured in the nanowell array indicating PSMA+ PSA+ (in red), PSMA−PSA+ (in yellow), PSMA+ PSA− (in green), and PSMA−PSA− (in blue).