Figure 6 from PSA Secretion from Single Circulating Tumor Cells of Metastatic Castration-Naïve Prostate Cancer Patients

PSA secretions (pg/cell) from single CTC and total CTC captured in nanowell array from patients with mCNPC (n = 18). A, The PSMA⁺ PSA⁺ (in red) and PSMA⁻PSA⁺ (in yellow) indicate the two subpopulations of CTC that secrete. The PSMA⁺ PSA⁻ (in green) and PSMA⁻PSA⁻ (in blue) indicate the two subpopulations of CTC that are non-secreting cells. The serum PSA (ng/mL) and the CTC in 7.5 mL of blood are indicated on the secondary x-axis. B, Total counts of the CTC captured in the nanowell array indicating PSMA⁺ PSA⁺ (in red), PSMA⁻PSA⁺ (in yellow), PSMA⁺ PSA⁻ (in green), and PSMA⁻PSA⁻ (in blue).