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August 18, 2025Open Access

Figure 1 from PSA Secretion from Single Circulating Tumor Cells of Metastatic Castration-Naïve Prostate Cancer Patients

Eshwari Dathathri Fikri Abali Michiel Stevens Richell Booijink Tanja C. van Dijk Khrystany T. Isebia John W.M. Martens Jaco Kraan Nick Beije Martijn P. Lolkema Peter A.W. te Boekhorst Paul Hamberg Brigitte C.M. Haberkorn Danny Houtsma Joan van den Bosch Wendy M. van der Deure Ruchi Bansal Leon W.M.M. Terstappen

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Key Points

CTCs were classified based on CK and PSMA, with significant proportions identified across groups.
The analysis showed a Spearman correlation coefficient of 0.5 for CK+ and PSMA+ CTCs, suggesting a moderate relationship between these markers.
Enumeration involved samples from 18 metastatic castration-naïve prostate cancer patients, enhancing understanding of CTCs in this context.
Findings highlight the importance of CTCs as potential biomarkers for monitoring prostate cancer progression.

Implication

Enumeration of CTCs based on CK and PSMA expression reveals significant correlations in prostate cancer patients, indicating potential diagnostic value.

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Cite This Study

Dathathri et al. (2025) studied this question.

synapsesocial.com/papers/68af4328ad7bf08b1ead2277 https://doi.org/10.1158/2767-9764.29929888

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1Figure 6 from PSA Secretion from Single Circulating Tumor Cells of Metastatic Castration-Naïve Prostate Cancer Patients2025
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