Nikolaos Dagres works in Electrophysiology affiliated with Leipzig University.
Prof. Dr. Nikolaos Dagres is Senior Consultant at the University Outpatient Clinic CCM and Co-Spokesperson of the DHZC Study Centre at Deutsches Herzzentrum der Charité in Berlin. He previously worked in the Department of Electrophysiology at Heart Center Leipzig at the University of Leipzig. He contributes to ESC and EHRA guidelines on atrial fibrillation and coordinates research on ICD implantation after myocardial infarction through the PROFID project.
393 pubs · 45,849 cites · h-index 65
Dr. med.
University of Freiburg
1991
Senior Consultant, University Outpatient Clinic CCM | Co-Spokesperson, DHZC Study Centre
Deutsches Herzzentrum der Charité · 2024 - Present
PD Dr. med., Department of Electrophysiology
Heart Center Leipzig at University of Leipzig · 2010 - 2023
Heart RhythmTscholl et al.cohort
Three contemporary pulsed field ablation systems (CMAC, VLCC, and LTC) demonstrated comparable 12-month arrhythmia-free survival and high safety in real-world clinical practice, despite differences in procedural and ablation times.
EHJShamloo et al.cohort
Despite temporal increases, triple therapy uptake remained <10% post-MI; leaves open targeted interventions to address MRA underuse in routine care.
EHJShamloo et al.cohort
In post-MI patients, BMI shows a non-linear association with long-term sudden cardiac death risk, with the lowest risk at a BMI of 22.8 kg/m² and progressively increasing risk at higher BMI values.
EHJChiba et al.cohort
In the contemporary post-2016 era, ICD implantation in post-MI patients with LVEF ≤35% was not associated with a significant reduction in all-cause mortality compared to matched non-ICD patients, suggesting an attenuation of historical survival benefits due to modern medical therapy.
JACC AsiaChoi et al.review
This review compares AFib care in Europe and the Asia Pacific region, which together hold most of the world's 60 million patients. Practice splits in all six areas: risk factors, lifestyle and other conditions, stroke prevention, rhythm control and ablation, digital tools and health systems. Blood thinner gaps have shrunk, yet gaps in funding, procedure capacity and digital access remain, and differences inside each region rival those between them. Closing these gaps will take resource adapted plans and sharing evidence across both regions.
Consultant in Cardiology, Emory University School of Medicine · Emory University School of Medicine
I do not understand the mechanism responsible for the electrocardiographic findings reported by Bruch and associates. Could it be that the definition of low amplitude (0.5 mv) used by Bruch's group was too low? During the past few years, I have used the data provided by Odom and colleagues to calculate the normal range of QRS voltage. The normal range for the QRS voltage of adults with normal hearts is calculated by the 12-lead QRS amplitude, and is 80-185 millimeters. I prefer this method because there are few studies indicating the low end of the normal range.
Journal of the American College of CardiologyBruch et al.
Electrophysiology · Humboldt-Universität zu Berlin
Our findings do not mean that ICD use in myocardial infarction patients with severely reduced pump function is generally no longer beneficial. Rather, they show that the current strategy of prophylactically implanting a defibrillator in these patients cannot be a one-size-fits-all solution. Each case must be considered individually.
European Heart JournalShamloo et al.
EHJSambola et al.cohort
Confirms in a large prospective registry that vegetation size >10 mm alongside key clinical, microbiological, and haemodynamic factors independently predicts embolic events and 30-day mortality in left-sided infective endocarditis, supporting early surgical risk stratification.
Heart Failure / Cardiomyopathy · Darmstadt University of Applied Sciences
Our data show that most of the improvement reported by patients does not appear to be attributable to catheter ablation itself, but rather to factors such as a placebo effect or adjustments to their medication. Current guidelines recommend catheter ablation primarily to prevent the recurrence of atrial fibrillation and improve quality of life. However, our study shows that the effect of the ablation itself does not adequately explain the improvement in quality of life.
LancetWachter et al.RCT · ESC 2026
PVI-SHAM-AF tested catheter ablation against a sham procedure in 262 patients with symptomatic AFib. At six months, the mean quality of life score rose from 61.3 to 81.1 with ablation and from 59.2 to 74.9 with the sham procedure. That difference was not significant, and 12 month follow up is ongoing.
EHJMach et al.Guideline
Revises lipid management for ACS, HIV, and statin-intolerant patients; extends 2019 ESC/EAS guidelines with post-2019 trial data.
EHJHabib et al.cohort
Infective endocarditis remains a life-threatening disease with a 17.1% in-hospital mortality rate, and failure to perform indicated surgery is an independent predictor of death.
Atrial Fibrillation Management and Outcomes · Saint Thomas Health
Evidence also suggests that women with AF have a delayed referral pattern compared with men and fail more antiarrhythmic medications before catheter ablation. Delaying the time to ablation could promote a higher AF or comorbidity burden at the time of ablation, which may have resulted in more electrical and structural remodeling.
Journal of the American College of CardiologyDagres et al.
EP EuropaceHeil et al.cohort
Apparent higher AF recurrence in women after cryoballoon ablation may reflect lower cryothermal exposure; leaves open whether sex-specific dosing improves outcomes.
European Journal of Heart FailureMoersdorf et al.RCT
Supports ablation plus GDMT in end-stage HF with AF; extends CASTLE-HTx with quantified 3-year net benefit.
European Heart Journal - Digital HealthChiba et al.cohort
May refine ICD therapy prediction in recipients; extends discrimination models via external validation but leaves clinical adoption open.
EHJHadwiger et al.cohort
Supports CRT-P consideration to avoid defibrillator risks in selected patients; leaves open randomized confirmation of equivalence.
EHJSeewoester et al.cohort
The novel P-Wave Area Index (PWAi) is a strong non-invasive predictor of low voltage areas prior to AF ablation, which may help individualize ablation strategies.
Journal of Clinical MedicinePlappert et al.cohort
Supports broader ILR use beyond syncope and cryptogenic stroke; extends real-world evidence to presyncope, risk stratification, and post-ablation monitoring.
EHJShamloo et al.editorial
This editorial discusses the long-term outcomes of subcutaneous implantable cardioverter-defibrillators based on the French nationwide HONEST study.
JACC AdvancesPeters et al.cohort
Observational data describe pregnancy outcomes in impaired LVF; leaves open optimal risk stratification and management strategies.
