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August 18, 2025Open Access

Figure 1 from PSA Secretion from Single Circulating Tumor Cells of Metastatic Castration-Naïve Prostate Cancer Patients

Key Points

CTCs were classified based on CK and PSMA, with significant proportions identified across groups.
The analysis showed a Spearman correlation coefficient of 0.5 for CK+ and PSMA+ CTCs, suggesting a moderate relationship between these markers.
Enumeration involved samples from 18 metastatic castration-naïve prostate cancer patients, enhancing understanding of CTCs in this context.
Findings highlight the importance of CTCs as potential biomarkers for monitoring prostate cancer progression.

Abstract

Enumeration of CTCs based on CK and PSMA expression. A, Graph depicting the number of DAPI+ CD45− CTCs as the following groups: CK−PSMA+ (yellow), CK+ PSMA−(orange), and CK+ PSMA+ (red) in the DLA aliquot of the 18 patients. B, Correlation of the number of CK+ and PSMA+ CTCs (Spearman coefficient ρ = 0.5).

Figure 1 from PSA Secretion from Single Circulating Tumor Cells of Metastatic Castration-Naïve Prostate Cancer Patients

Key Points

Abstract

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