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September 10, 2025Open Access

Figure S14 from PPARδ Orchestrates a Prometastatic Metabolic Response to Microenvironmental Cues in Pancreatic Cancer

Pharmacological modulation of ppar-δ inhibits metastasis in pancreatic cancer, indicating its pivotal role.
Meta-analysis showed enhanced invasion and metastasis in vivo, with the highly metastatic PDX CTCA model.
Research utilized advanced techniques in pharmacological modulation to study ppar-δ effects on tumor behavior.
Findings suggest targeting ppar-δ may offer new therapeutic avenues for pancreatic cancer management.

Effects of pharmacological modulation of PPAR-δ on invasion and metastasis in vivo, using the highly metastatic PDX CTCA

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Parejo-Alonso et al. (Tue,) studied this question.

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