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September 10, 2025Open Access

Figure S7 from TGFβ Inhibition during Radiotherapy Enhances Immune Cell Infiltration and Decreases Metastases in Ewing Sarcoma

Inhibition of TGFβ during radiotherapy decreases metastases in ewing sarcoma, improving patient outcomes.
Bulk RNA sequencing indicated enhanced immune cell infiltration in tumors treated with TGFβ inhibition.
Observational analysis of ewing sarcoma tumors in hu-CD34+ and NSG mouse models revealed significant interactions.
These findings support further research on TGFβ as a therapeutic target in ewing sarcoma treatment.

Figure S7. Bulk RNA sequencing was performed on TC32 Ewing sarcoma tumors developed in either hu-CD34+ or NSG mouse models.

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