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October 12, 2025Open Access

A Brief Study on Papaya (Carica Papaya) – A Review

GSGayatri Ashok ShirsatSaraswati Dental College and Hospital MJMohini Raju JejurkarSaraswati Dental College and Hospital PBPrasad Sopan BhongalSaraswati Dental College and Hospital

Key Points

Carica papaya shows significant antibacterial and anti-inflammatory effects on acne vulgaris, highlighting its potential as a natural treatment.
The presence of bioactive compounds like papain and flavonoids provides papaya with keratolytic and antioxidant properties, enhancing treatment efficacy.
Herbal-based formulations utilizing carica papaya offer a safer alternative to synthetic treatments often linked to irritation and resistance.
The review focuses on pharmacognosy and phytochemistry associated with papaya, supporting its incorporation in polyherbal anti-acne cream.

Abstract

Acne vulgaris is a multifactorial inflammatory disorder of the pilosebaceous unit, primarily affecting adolescents and young adults. Synthetic anti-acne treatments, though effective, often cause irritation and antibiotic resistance. Consequently, herbal-based formulations are gaining popularity due to their safety and efficacy. Carica papaya (papaya) is a tropical fruit-bearing plant known for its remarkable dermatological and pharmacological properties. Its bioactive compounds—papain, chymopapain, flavonoids, alkaloids, and vitamins—exhibit antibacterial, antioxidant, keratolytic, and anti-inflammatory actions. This review emphasizes the pharmacognosy, phytochemistry, pharmacological activities, and potential of papaya in polyherbal anti-acne cream formulations

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