The Universal Resonance Model proposes a geometry-based ontology of chronic disease where disease behavior is governed by instability geometry and systemic resonance, not molecular defects or static labels.
This document presents the official Foundational Declaration of the Universal Resonance Model (URM), Version 1.0. URM establishes a geometry-based ontology of disease, defining pathology as a dynamical instability regime in a coupled, multiscale biological system. Rather than focusing on molecular identity or organ-specific classification, the model describes chronic disease behaviour through restoring curvature (λ₁), variance (σ²), temporal persistence (ρ(τ)), phase delay (Δτ), and cross-system coupling (κ). The Reset Index (RI) formalizes instability proximity and defines the temporal conditions under which therapeutic leverage is maximal. This declaration articulates the core ontological and mathematical principles of URM in a concise form and serves as the foundational reference document for the broader URM body of work. This document is conceptually expanded in:The Universal Resonance Model (URM): A Foundational Framework for Chronic Disease Dynamics (DOI: https://doi.org/10.5281/zenodo.18698512)
Anita Domargård (Thu,) reported a other. The Universal Resonance Model proposes a geometry-based ontology of chronic disease where disease behavior is governed by instability geometry and systemic resonance, not molecular defects or static labels.