What question did this study set out to answer?

The aim is to evaluate the efficacy and safety of hazelnut oral immunotherapy (H-OIT) in children with hazelnut allergies (HA).

February 25, 2026

Hazelnut oral immunotherapy in children: An Italian single-center retrospective cohort study.

Key Points

The aim is to evaluate the efficacy and safety of hazelnut oral immunotherapy (H-OIT) in children with hazelnut allergies (HA).
Conducted a retrospective cohort study at a single center
Included children diagnosed with hazelnut allergies
Analyzed rates of discontinuation and anaphylactic events
One quarter of patients maintained a lower, partial dose of H-OIT
Overall safety profile deemed acceptable despite anaphylactic events
High rate of discontinuation was noted among participants

Abstract

H-OIT may be an effective treatment option for children with HA despite the high discontinuation rate. One quarter of patients remained on a lower, partial maintenance dose. Although the overall safety profile of H-OIT seems acceptable, anaphylactic events represent a significant burden for families and must be carefully considered when weighing the risks and benefits of OIT.

Hazelnut oral immunotherapy in children: An Italian single-center retrospective cohort study.

Key Points

Abstract

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