Identification of the Novel HLA‐DQB1*06:549 Allele by Next‐Generation Sequencing

Key Points

• The central aim is to identify and characterize the HLA-DQB1*06:549 allele.
• Utilized next-generation sequencing for allele identification
• Focused on nucleotide substitutions in exon 2
• Compared findings to HLA-DQB1*06:02:01:01 allele
• Identified a nucleotide substitution in HLA-DQB1*06:549
• Confirmed genetic variation from HLA-DQB1*06:02:01:01
• Potential implications for understanding immune response