Postoperative Adjuvant Chemoradiotherapy ± PD-1 Inhibitor for Locally Advanced Head and Neck Squamous Cell Carcinoma.

Key Points

• To assess the role of PD-1 inhibitors alongside chemoradiotherapy in improving outcomes for head and neck squamous cell carcinoma.
• Evaluated treatment outcomes of PD-1 inhibitors in combination with chemoradiotherapy.
• Analyzed variations in efficacy based on tumor characteristics.
• Compared outcomes in patients receiving only chemoradiotherapy versus those receiving the combination.
• PD-1 inhibitors showed less impact on tumors with favorable treatment outcomes.
• Patients with better treatment responses from chemoradiotherapy gained fewer benefits from PD-1 inhibitors.