Cryptococcal Antigenemia in South African Children Living With HIV | Synapse
March 3, 2026
Cryptococcal Antigenemia in South African Children Living With HIV
Key Points
CrAg prevalence in children with CD4 <100 cells/µL stands at 4.7%, similar to 5.8% in adults.
Assessment using cryptococcal antigenemia screening guidelines emphasizes the need for inclusion of all children.
Comparative analysis shows that early screening could lead to better health outcomes for HIV-positive children.
Extending the screening guidelines highlights a crucial need for improved interventions in pediatric HIV care.
Abstract
CrAg prevalence in children with CD4 <100 cells/µL is comparable to adults (4.7% and 5.8%, respectively). CrAg screening guidelines should be extended to include all children to improve outcomes.