Site-specific inverse associations between FGF23 levels and marrow adiposity content at the proximal femur in post-menopausal women

Key Points

• Higher levels of cFGF23 and iFGF23 correlate with lower proximal femur PDFF, particularly at the femoral neck.
• The study measured adiposity at specific sites, including the proximal femur and lumbar spine, finding site-specific relationships.
• Observational analysis focused on post-menopausal women and their proximal femur adipose content.
• These findings suggest that FGF23 may play a role in regulating marrow adiposity, but additional research is needed.