Spontaneous association of different forms of non-conjugated astatine-211 to serum albumin

Key Points

• Free astatine associates with serum albumin at a significantly higher level than iodine, improving its blood circulation time.
• This notable association suggests potential implications for improving drug delivery systems using free astatine.
• The investigation compares various forms of non-conjugated astatine specifically regarding their interaction with serum proteins.
• Findings may extend current understanding of astatine's pharmacokinetics in therapeutic applications.