What question did this study set out to answer?

To assess the clinical efficacy of fosfomycin against carbapenem-resistant Klebsiella pneumoniae in urinary tract infections.

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March 8, 2026Open Access

Susceptibility of carbapenem-resistant Klebsiella pneumoniae in urinary tract infections: clinical efficacy of fosfomycin

Key Points

To assess the clinical efficacy of fosfomycin against carbapenem-resistant Klebsiella pneumoniae in urinary tract infections.
Retrospective analysis of clinical data
Evaluation of treatment regimens including fosfomycin
Examination of treatment outcomes in patients with CR-Kp UTIs
Fosfomycin shows potential as a salvage treatment option
Efficacy varies depending on individual patient conditions
Limitations noted in study design, such as being single-center and retrospective

Abstract

Clinical experience may be feasible and needed to assess the efficacy of nitrofurantoin and TMP-SMX. Fosfomycin-including regimens may serve as a salvage treatment option for CR-Kp UTI in selected patients. However, the retrospective and single-center design of the study should be considered as a limitation.

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