A 55-year-old female with primary pulmonary diffuse large B-cell lymphoma presented with significant left atrial invasion and a high Ki-67 proliferative index (95%).
Highlights a rare case of primary pulmonary diffuse large B-cell lymphoma with cardiac extension into the left atrium, emphasizing the need for comprehensive imaging and immunophenotyping.
Absolute Event Rate: 0% vs 0%
Abstract: Primary pulmonary lymphoma is an uncommon entity, accounting for <1% of all non-Hodgkin lymphomas and <0.5% of primary lung tumors. Cardiac extension via the pulmonary vein is exceptionally rare. We report a case of a 55-year-old postmenopausal female with hypothyroidism and rheumatoid arthritis who presented with progressive dyspnea and significant weight loss. Imaging revealed a large fluorodeoxyglucose-avid mass in the right lower lobe of the lung extending into the left atrium with tumor thrombus, mediastinal lymphadenopathy, and adrenal involvement. Histopathology and immunohistochemistry confirmed diffuse large B-cell lymphoma (DLBCL) with a high proliferative index (Ki-67: 95%). This case emphasizes the importance of comprehensive imaging and immunophenotyping in diagnosing atypical thoracic masses.
Mauryakrishna et al. (Wed,) reported a other. A 55-year-old female with primary pulmonary diffuse large B-cell lymphoma presented with significant left atrial invasion and a high Ki-67 proliferative index (95%).