Comparison of polydipsia and polyuria in dogs treated with once‐daily or divided twice‐daily oral prednisolone in 12 dogs

Key Points

• To compare the effects of once-daily and twice-daily dosages of prednisolone on polydipsia and polyuria in dogs.
• Observed 12 dogs under treatment for polydipsia and polyuria
• Compared once-daily and divided twice-daily dosing of prednisolone
• Measured urine specific gravity and osmolality for assessment of urine concentration.
• Once-daily dosing of prednisolone significantly reduced excessive water intake
• Urine specific gravity and osmolality showed interchangeable results in assessing urine concentration.