Does low-dose aspirin prevent cardiovascular disease in healthy older adults?
Low-dose aspirin is not effective for primary cardiovascular prevention in healthy older adults and significantly increases the risk of major hemorrhage.
The use of low-dose aspirin as a primary prevention strategy in older adults resulted in a significantly higher risk of major hemorrhage and did not result in a significantly lower risk of cardiovascular disease than placebo. (Funded by the National Institute on Aging and others; ASPREE ClinicalTrials.gov number, NCT01038583 .).
McNeil et al. (Sun,) studied this question.