Cardiac Inflammation Contributes to Changes in the Extracellular Matrix in Patients With Heart Failure and Normal Ejection Fraction

Population

Patients with Heart Failure and Normal Ejection Fraction (HFNEF)

Outcome

Extracellular matrix (ECM) accumulation and diastolic dysfunctionsurrogate

Cardiac inflammation plays a pathophysiological role in HFNEF by promoting extracellular matrix accumulation and subsequent diastolic dysfunction.

Cardiac inflammation contributes to diastolic dysfunction in HFNEF by triggering the accumulation of ECM.

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Circulation Heart Failure

Franklin University

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