Does antihypertensive use reduce the risk of dementia in late life compared to untreated hypertension?
Treatment of hypertension in late life is associated with a reduced risk of dementia, lowering the risk to levels comparable to healthy controls.
This individual patient data meta-analysis of longitudinal cohort studies found that antihypertensive use was associated with decreased dementia risk compared with individuals with untreated hypertension through all ages in late life. Individuals with treated hypertension had no increased risk of dementia compared with healthy controls.
Lennon et al. (Tue,) studied this question.