Discovery of the Novel HLA‐C*08:01:44 Allele in a Taiwanese Individual

Key Points

• The research aims to identify novel allelic variations in the HLA-C gene, focusing on HLA-C*08:01:44.
• Genetic sequencing to analyze nucleotide variations
• Identification of specific codon substitutions
• Comparison against known HLA-C alleles
• Discovery of HLA-C*08:01:44 resulting from a nucleotide substitution at codon 105
• Characterization of the novel allele highlights genetic diversity in the Taiwanese population