The BP98AL tail-cuff device recorded significantly lower systolic blood pressure than the UR5000 device in all rat strains, despite a strong correlation (r=0.896) between the two methods.
Does the BP98AL tail-cuff device provide comparable systolic blood pressure measurements to the UR5000 device in hypertensive and normotensive rats?
The BP98AL tail-cuff device correlates well with the UR5000 for measuring systolic blood pressure in rats, but yields significantly lower absolute values, which must be accounted for in long-term studies.
Effect estimate: r=0.896
p-value: p=<0.01
The tail-cuff method is commonly used to measure blood pressure in rats. We examined two types of tailcuff devices, the BP98AL and UR5000 in hypertensive rats. Indirect systolic blood pressure（ SBP） measured using the tail-cuff method with the BP98AL correlated well with the SBP recorded with the UR5000. The SBP recorded using BP98AL was significantly lower than that measured using UR5000 in male spontaneously hypertensive rats, stroke-prone spontaneously hypertensive rats, and normotensive Wistar Kyoto rats at 8 weeks of age. These results will be useful for indirectly determining SBP in long-term studies using hypertensive rats.
Yasui et al. (Tue,) conducted a other in Hypertension (Animal Model) (n=60). BP98AL tail-cuff device vs. UR5000 tail-cuff device was evaluated on Systolic blood pressure (SBP) (r=0.896, p=<0.01). The BP98AL tail-cuff device recorded significantly lower systolic blood pressure than the UR5000 device in all rat strains, despite a strong correlation (r=0.896) between the two methods.