Investigating the impact of problematic evidence on clinical practice guidelines and associated patient outcomes (VITALITY Study II): protocol

Key Points

• This investigation aims to explore the effects of problematic evidence on clinical practice guidelines and subsequent patient outcomes.
• Analyse existing literature on clinical practice guidelines.
• Evaluate the influence of evidence on patient care decisions.
• Identify shortcomings in current clinical guidelines.
• Highlight gaps in evidence that affect guidelines.
• Demonstrate potential negative impacts on patient outcomes.
• Suggest recommendations for improving evidence use in guidelines.