Fibrotic remodeling of subepicardial adipose tissue, potentially mediated by cytotoxic lymphocytes, may contribute to the structural substrate for atrial fibrillation.
Atrial fibrillation is associated with the fibrosis of subepicardial fatty infiltrates, a process in which cytotoxic lymphocytes might be involved. This remodelling of the atrial subepicardium could contribute to structural remodelling forming a substrate for AF.
Haemers et al. (Thu,) studied this question.