November 14, 2016Open Access
View Full PaperRandomized Trial of Bilateral versus Single Internal-Thoracic-Artery Grafts
Structured PICO
Does bilateral internal-thoracic-artery grafting reduce mortality or cardiovascular events compared to single internal-thoracic-artery grafting in patients undergoing CABG?
P
Population
Patients undergoing CABG
I
Intervention
Bilateral internal-thoracic-artery grafts
C
Comparator
Single internal-thoracic-artery grafts
O
Outcome
Mortality or the rates of cardiovascular events at 5 years of follow-uphard clinical
At 5 years of follow-up, bilateral internal-thoracic-artery grafting does not improve mortality or cardiovascular event rates compared to single grafting, but is associated with an increased risk of sternal wound complications.
Abstract
Among patients undergoing CABG, there was no significant difference between those receiving single internal-thoracic-artery grafts and those receiving bilateral internal-thoracic-artery grafts with regard to mortality or the rates of cardiovascular events at 5 years of follow-up. There were more sternal wound complications with bilateral internal-thoracic-artery grafting than with single internal-thoracic-artery grafting. Ten-year follow-up is ongoing. (Funded by the British Heart Foundation and others; ART Current Controlled Trials number, ISRCTN46552265 .).