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November 14, 2016New England Journal of Medicine389 citationsOpen Access

Randomized Trial of Bilateral versus Single Internal-Thoracic-Artery Grafts

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Why the study?

Does bilateral internal-thoracic-artery grafting reduce mortality or cardiovascular events compared to single internal-thoracic-artery grafting in patients undergoing CABG?

Population

Patients undergoing CABG

Comparison

Bilateral internal-thoracic-artery grafts vs Single internal-thoracic-artery grafts

Design

RCT

Follow-up

5 years

Authors

DTDavid P. TaggartDADouglas G. AltmanAGAlastair Gray

Discussion

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Overview

Bilateral grafting shows no 5-year mortality or event benefit versus single grafting and raises sternal wound risk; challenges routine use in CABG.

Structured PICO

Does bilateral internal-thoracic-artery grafting reduce mortality or cardiovascular events compared to single internal-thoracic-artery grafting in patients undergoing CABG?

P
Population
Patients undergoing CABG
I
Intervention
Bilateral internal-thoracic-artery grafts
C
Comparator
Single internal-thoracic-artery grafts
O
Outcome
Mortality or the rates of cardiovascular events at 5 years of follow-uphard clinical

At 5 years of follow-up, bilateral internal-thoracic-artery grafting does not improve mortality or cardiovascular event rates compared to single grafting, but is associated with an increased risk of sternal wound complications.

Cite This Study

Taggart et al. (2016) studied this question.

synapsesocial.com/papers/69d56e2b75589c71d767d46bhttps://doi.org/10.1056/nejmoa1610021
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