Plasma Concentrations and Genetic Variation of Matrix Metalloproteinase 9 and Prognosis of Patients With Cardiovascular Disease

Key Points

• To evaluate plasma MMP-9 concentrations as a predictor of cardiovascular mortality in coronary artery disease patients.
• Assessment of plasma MMP-9 concentration alongside other inflammatory markers in a clinical setup.
• Comparison of MMP-9 predictive value for mortality against existing markers.
• Plasma MMP-9 concentration was associated with increased cardiovascular mortality.
• The study suggests that MMP-9 may offer independent prognostic information alongside other markers.