March 31, 2003Circulation753 citationsOpen Access
View Full PaperPlasma Concentrations and Genetic Variation of Matrix Metalloproteinase 9 and Prognosis of Patients With Cardiovascular Disease
Key Points
- To evaluate plasma MMP-9 concentrations as a predictor of cardiovascular mortality in coronary artery disease patients.
- Assessment of plasma MMP-9 concentration alongside other inflammatory markers in a clinical setup.
- Comparison of MMP-9 predictive value for mortality against existing markers.
- Plasma MMP-9 concentration was associated with increased cardiovascular mortality.
- The study suggests that MMP-9 may offer independent prognostic information alongside other markers.
Abstract
Plasma MMP-9 concentration was identified as a novel predictor of CV mortality in patients with coronary artery disease. Whether it provides independent prognostic information compared with other inflammatory markers will have to be additionally assessed.